Disseminated histoplasmosis successfully treated with amphotericin B.

Nonsurgical treatment of Histoplasma endocarditis involving a bioprosthetic valve.

Endocardial involvement associated with disseminated histoplasmosis has been infrequently documented, especially among patients with prosthetic valves. The therapeutic approach to these patients is also not yet clearly defined. A 54-year-old man with prosthetic valve endocarditis due to histoplasmosis was successfully treated with amphotericin B. A review of the literature suggests that the opt...

Disseminated histoplasmosis treated with amphotericin B. Report of a case.

Disseminated histoplasmosis: a rare clinical phenotype with difficult diagnosis

We describe a rare and interesting case of a 37-year-old man who presented with an intermittent fever, progressive cytopenia, and hepatosplenomegaly. Histopathological examination of a bone marrow smear revealed haemophagocytes and intracellular yeast-like Histoplasma capsulatum (H. capsulatum); thus, we prolonged the blood culture duration to detect fungi, and H. capsulatum was detected in the...

A case of cerebral histoplasmosis in an immunocompetent host successfully treated with voriconazole

— Histoplasma capsulatum var. capsulatum is a neurotropic dimorphic fungus. The majority of immunocompetent infected individuals have either no symptoms or a very mild illness. CNS involvement is observed in 5% to 10% of patients, mostly in case of disseminated histoplasmosis and/or in association with immunecompromising conditions. Radiologic differential diagnosis of a ring-enhancing intrapar...

Oropharyngeal histoplasmosis: report of eleven cases and review of the literature.

INTRODUCTION Histoplasmosis is a systemic mycosis endemic in Brazil, especially in the State of Rio Grande do Sul, where Histoplasma capsulatum was isolated from the soil. H. capsulatum may compromise unusual areas, including the oropharynx, particularly in patients presenting disseminated histoplasmosis; which is associated with a state of immunosuppression, such as AIDS. METHODS During data...